Sakae naa extract | Combretum quadrangulare | 25x – 5 g

Sakae Naa Extract 25x is a concentrated botanical preparation made from the leaves of Combretum quadrangulare, a Southeast Asian tree with a long history in the traditional herbal practices of Thailand, Laos and Myanmar.

Known locally as sakae naa, the plant has traditionally been incorporated into various cultural and folk practices across its native range. Each 5 g pack is supplied in airtight, hermetically sealed packaging to help protect the extract from moisture and environmental exposure.

About Sakae Naa (Combretum quadrangulare)

Combretum quadrangulare is a member of the Combretaceae family. It is a medium-sized to large tree naturally occurring across parts of mainland Southeast Asia, including Thailand, Laos, Myanmar, Cambodia and Vietnam.

The species is recognisable by its distinctive four-angled young branches, lance-shaped leaves, small pale flowers and winged fruits. It commonly occurs near rivers and in secondary woodland, open areas and other disturbed habitats.

The plant has long been familiar to rural communities throughout the regions in which it grows naturally.

Traditional and Cultural Background

The leaves of Combretum quadrangulare have a history of traditional use in Thailand, Laos and Myanmar. Historical ethnobotanical accounts describe the leaves being incorporated into smoking and chewing practices in rural communities.

Other parts of the plant have also featured in traditional Southeast Asian herbal preparations. For example, the seeds have historically been used in folk preparations associated with digestive and intestinal concerns.

The plant’s cultural importance has continued into more recent times, particularly in rural areas of Thailand, where sakae naa has remained part of regional botanical traditions. Traditional use is based on cultural and historical practice and should not be interpreted as evidence of proven medical effects.

Naturally Occurring Constituents

Research into Combretum quadrangulare has identified a variety of naturally occurring plant constituents, including:

• Combretol and related compounds reported in Combretum species
• Tannins, including ellagic acid-related compounds
• Flavonoids, including compounds such as vitexin
• Other botanical constituents and alkaloid fractions, the complete profile of which remains under investigation

The concentration of individual compounds may vary depending on factors such as geographical origin, harvesting conditions, plant maturity and extraction technique.

25x Extraction

The 25x designation describes the starting-material-to-extract ratio. Approximately 25 g of dried sakae naa leaf material is processed to produce 1 g of concentrated extract. Water and ethanol extraction can be used to obtain soluble botanical constituents from the leaves. The resulting extract is then dried and milled into a fine, uniform powder.

A 25x ratio indicates a higher concentration of starting botanical material by weight compared with raw leaf material. It does not mean that every individual constituent is present at precisely 25 times the concentration.

Traditional-Style Preparation

The extract can be incorporated into a warm herbal infusion. For a simple preparation:

• Follow the manufacturer’s recommended serving instructions.
• Mix the appropriate amount of extract with hot water.
• Allow the preparation to steep before consuming.
• Honey may be added to taste.

Historically, the leaves have also been associated with smoking and chewing practices. Smoking botanical material can produce harmful combustion products and is not considered a risk-free method of consumption. If you choose to use botanical products, follow the product label and applicable local regulations rather than relying on historical preparation methods.

Pack Contents

Each package contains:

• 5 g Sakae Naa Extract 25x
• Botanical source: Combretum quadrangulare
• Concentrated leaf extract
• Hermetically sealed packaging

Storage and Safety

Store in a cool, dry and dark location away from direct sunlight, heat and humidity. Keep the packaging securely closed and out of reach of children.

Do not use during pregnancy or breastfeeding. If you take prescription medicines, have an existing medical condition or are uncertain about possible interactions, consult a doctor or pharmacist before use.

Avoid driving or operating machinery if you experience drowsiness, dizziness or impaired concentration.

This product is a botanical extract and is not a medicinal product. It is not intended to diagnose, treat, cure or prevent any disease and should not replace a varied and balanced diet.

Always check the laws and regulations applicable to Combretum quadrangulare and botanical extracts in your country before purchasing or using the product.